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Lint: john-cunningham-virus-1

Headings Spacing
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"History and etymology "

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Acronyms
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"John Cunningham virus (JC virus), also known as human polyomavirus 2, is a ubiquitous double-stranded DNA virus of the polyomaviridae family 1. In immunocompromised individuals, reactivation can lead to a variety of disease of the central nervous system, the most common of which is progressive multifocal leukoencephalopathy (PML)."

Line 1:35 · 'JC' has no definition. Spell it out if it's unfamiliar to the audience.

"Infection with JC virus, usually asymptomatic, results in latent infection in various organs and tissues of the body. When patients are immunocompromised, the virus can reactivate and migrate to the central nervous system, with a predilection for glial cells, thus resulting in the classical leukoencephalopathy of progressive multifocal leukoencephalopathy 6."

Line 6:19 · 'JC' has no definition. Spell it out if it's unfamiliar to the audience.

"JC virus granule cell neuronopathy (rare)"

Line 14:7 · 'JC' has no definition. Spell it out if it's unfamiliar to the audience.

"JC virus meningitis (rare)"

Line 18:4 · 'JC' has no definition. Spell it out if it's unfamiliar to the audience.

"JC virus encephalopathy (very rare)"

Line 25:4 · 'JC' has no definition. Spell it out if it's unfamiliar to the audience.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"History and etymology "

Line 32:1 · "History and etymology " is not a recognised heading for this article type.
Semicolons
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"It has been reported that ~70% of adults have been exposed to this virus; however, no significant clinical syndrome has been associated with this acquisition in the majority of immunocompetent hosts 1."

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Inline EG
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"Numerous causes of immunosuppression have been implicated in reactivation of the virus, including HIV/AIDS, malignancy (e.g. lymphoma), immonusuppressants, and immunomodulators (e.g. natalizumab for multiple sclerosis)."

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