"Lemierre syndrome, also known as postanginal septicaemia, refers to thrombophlebitis of the internal jugular vein(s) with distant metastatic anaerobic septicaemia in the setting of an initial bacterial oropharyngeal infection such as pharyngitis/tonsillitis, with extension into the lateral pharyngeal spaces of the neck, with or without peritonsillar or retropharyngeal abscess. Diagnosis is made based on clinical, microbiological and radiological investigations."
"It is named after André-Alfred Lemierre (1875–1956) 11, a French bacteriologist who described the typical features of the disease in 1936 based on a case series of 20 patients 3. However, Courmont and Cade first described the condition in 1900 as "human necrobacillosis" 11."
"It is named after André-Alfred Lemierre (1875–1956) 11, a French bacteriologist who described the typical features of the disease in 1936 based on a case series of 20 patients 3. However, Courmont and Cade first described the condition in 1900 as "human necrobacillosis" 11."
"An anaerobic Gram-negative bacillus, Fusobacterium necrophorum, is responsible for a majority (80%) of cases of Lemierre syndrome, and gives rise to the term necrobacillosis 1. Fusobacterium necrophorum is a commensal organism of the upper respiratory tract. In up to one-third of patients, polymicrobial bacteraemia is demonstrated, and anaerobic streptococci and other miscellaneous gram-negative anaerobes are also found frequently 8. Reports contain meticillin-resistant S. aureus (MRSA) as well 9. The causative bacteria are thought to spread directly from pharyngitis in the peritonsillar space to nearby tonsillar and internal jugular veins with subsequent septic thrombophlebitis."
"Lemierre syndrome, also known as postanginal septicaemia, refers to thrombophlebitis of the internal jugular vein(s) with distant metastatic anaerobic septicaemia in the setting of an initial bacterial oropharyngeal infection such as pharyngitis/tonsillitis, with extension into the lateral pharyngeal spaces of the neck, with or without peritonsillar or retropharyngeal abscess. Diagnosis is made based on clinical, microbiological and radiological investigations."
"Lemierre syndrome, also known as postanginal septicaemia, refers to thrombophlebitis of the internal jugular vein(s) with distant metastatic anaerobic septicaemia in the setting of an initial bacterial oropharyngeal infection such as pharyngitis/tonsillitis, with extension into the lateral pharyngeal spaces of the neck, with or without peritonsillar or retropharyngeal abscess. Diagnosis is made based on clinical, microbiological and radiological investigations."
"It is named after André-Alfred Lemierre (1875–1956) 11, a French bacteriologist who described the typical features of the disease in 1936 based on a case series of 20 patients 3. However, Courmont and Cade first described the condition in 1900 as "human necrobacillosis" 11."
"Since the advent of antibiotics, the incidence of Lemierre syndrome has reduced significantly, now affecting between 0.6 and 2.3 per million people. Lemierre syndrome classically affects young, healthy individuals, with 70% of patients between the ages of 16 and 25 years. There is a slight male predominance."
"If unrecognised and untreated, systemic dissemination can occur with a dismal prognosis; studies from the modern era still report mortality rates as high as 18% 8. Treatment is usually intravenous antibiotics. Surgical drainage is reserved for non-resolving abscesses 12. Anticoagulation may be used on a case-by-case basis, especially if there is evidence of dural venous sinus thrombosis 12."
"History and etymology"