"T2/FLAIR: high signal"
"T1: iso/low signal"
"DWI: diffusion restriction with high signal on DWI and low ADC values."
"T1 C+ (Gd): no enhancement"
"DWI: diffusion restriction with high signal on DWI and low ADC values."
"splenium of corpus callosum high signal intensity (MERS type 1)"
"diffuse involvement of the corpus callosum and bilateral symmetrical white matter/centrum semiovale lesions of high signal (MERS type 2)"
"The exact pathophysiology of MERS is unknown but various mechanisms have been proposed. Intra-myelinic oedema, and interstitial oedema in tightly packed fibres, a transient inflammatory infiltrate, vascular redistribution, arginine vasopressin suppression. Hypotonic hyponatraemia could lead to the entry of water into the brain, causing the transient diffusion restriction seen on MRI 1,2."
"demyelinating disease (e.g. ADEM)"
Expected headings
"Diagnostic criteria"
"demyelinating disease (e.g. ADEM)"
"toxic encephalopathy (e.g. methotrexate encephalopathy)"