"Ollier disease is seen in both sexes without gender predilection and usually becomes apparent by early childhood 3,4,. The condition is non-hereditary and is thought to occur as a result of random and spontaneous mutations."
"The aetiology of enchondromatosis has been associated with post-zygote state mutations during development. More interestingly, it has been reported that the PTHrP (parathyroid hormone-related protein) receptor has been implicated as a gene responsible for cases of enchondromatosis in patients with a family history of mild skeletal dysplasia in their male parents."
"It is named after Louis Xavier Édouard Léopold Ollier (1830-1900), a French orthopaedic surgeon 9."
Expected headings
"Associations"
"There is an increased risk of chondrosarcoma occurring later in life. The risk has been reported to be up to 25-30% at 40 years 1,2. Additionally, there is an increased risk of developing gliomas, pancreatic and juvenile granulosa cell tumours of the ovary 7,8."
"There is an increased risk of chondrosarcoma occurring later in life. The risk has been reported to be up to 25-30% at 40 years 1,2. Additionally, there is an increased risk of developing gliomas, pancreatic and juvenile granulosa cell tumours of the ovary 7,8."