"T1: isointense to muscle"
"T2: hyperintense"
"T1 C+ (Gd): avid enhancement"
"Most cases are sporadic. However, reports of familial occurrence suggest a possible autosomal dominant or recessive inheritance in some cases of infantile myofibromatosis, which have been linked to mutations in the PDGFR-beta and NOTCH3 genes 2."
Expected headings
"Subtypes"
"They can be asymptomatic. If present, symptoms and signs are non-specific 1. Cutaneous myofibromas may present as purplish macules, resembling a vascular neoplasm."
"In children, there is a predilection for the head and neck regions > trunk > lower extremities > upper extremities > viscera. Involved organs include the lungs, heart, gastrointestinal tract, liver, kidney, pancreas, or central nervous system."
"In adults, myofibromas prefer the dermis, subcutis, or oral cavity, which are more common than deeper lesions in bone, muscle, or aponeurosis. Osseous lesions usually involve craniofacial bones."
"There are three main subtypes of myofibromatosis 1:"