"Visual symptoms such as decreased visual acuity and papilloedema may occur, reflecting mass effect and impaired CSF flow. Endocrine or hypothalamic manifestations can also appear depending on tumour spread along the pineal–suprasellar axis 4."
"These tumours typically express OCT3/4 and CD30, which are reliable markers for identifying embryonal carcinoma. Cytokeratin positivity is also reported in intracranial cases. PLAP expression may be variable. According to CNS germ cell tumour guidelines, embryonal carcinoma also shows SOX2 positivity, helping distinguish it from germinoma, and may demonstrate low-level reactivity for AFP or HCG when minor differentiated components are present."
"These tumours typically express OCT3/4 and CD30, which are reliable markers for identifying embryonal carcinoma. Cytokeratin positivity is also reported in intracranial cases. PLAP expression may be variable. According to CNS germ cell tumour guidelines, embryonal carcinoma also shows SOX2 positivity, helping distinguish it from germinoma, and may demonstrate low-level reactivity for AFP or HCG when minor differentiated components are present."
"These tumours typically express OCT3/4 and CD30, which are reliable markers for identifying embryonal carcinoma. Cytokeratin positivity is also reported in intracranial cases. PLAP expression may be variable. According to CNS germ cell tumour guidelines, embryonal carcinoma also shows SOX2 positivity, helping distinguish it from germinoma, and may demonstrate low-level reactivity for AFP or HCG when minor differentiated components are present."
Expected headings
"Immunohistochemistry"