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Lint: primary-lateral-sclerosis

Illusions
warning

"Similar to amyotrophic lateral sclerosis, a paucity of effective treatment options exist. Prognosis much much better than other forms of motor neurone disease, with near-normal life expectancies reported 4."

Line 10:104 · 'much' is repeated!
Litotes
warning

"hereditary spastic paraplegia: typically presents at an earlier age, does not have bulbar involvement, upper limb involvement is unusual, and may have positive genetic testing 1"

Line 14:89 · Consider using 'lack(s)' instead of 'not have'
Acronyms
warning

"HTLV-1-associated myelopathy: positive HTLV-1 serology 1"

Line 18:11 · 'HTLV' has no definition. Spell it out if it's unfamiliar to the audience.

"HTLV-1-associated myelopathy: positive HTLV-1 serology 1"

Line 18:54 · 'HTLV' has no definition. Spell it out if it's unfamiliar to the audience.