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Lint: proteus-syndrome

Citation Punctuation Sup
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"Diagnosis is confirmed by genetic testing for the somatic AKT1 mutation in the affected tissues (not blood) 7."

Line 48:112 · Punctuation after citations should never be superscripted. '<sup>7.</sup>'
Colons
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"To consider a diagnosis of Proteus syndrome, the patient should have all three of the general characteristics in addition to some specific characteristics. The specific characteristics are grouped into three categories: A, B, and C. Diagnosis of Proteus syndrome requires all three general features to be present and either one feature from category A, or two features from category B, or three features from category C 9,10."

Line 3:222 · The first word after a colon should almost always be lowercase. In this case, it's not: ': A, B'.
Strong
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"General criteria (all should be present)"

Line 4:4 · Generally, don't use bold in text: '<strong>General criteria</strong>'

"Specific criteria"

Line 10:4 · Generally, don't use bold in text: '<strong>Specific criteria</strong>'
EG List And
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"abnormal facial features, e.g. dolichocephaly, long face, down slanting palpebral fissures and/or minor dropping of the eyelids (ptosis), low nasal bridge, anteverted nares and open mouth at rest"

Line 44:34 · An e.g. list gives selected examples, so it should not end with 'and' or 'or': 'e.g. dolichocephaly, long face, down slanting palpebral fissures and/or'.
Oxford Comma
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"vascular malformations: capillary, venous or lymphatic"

Line 43:39 · Use the Oxford comma in 'capillary, venous or lymphatic'.
Semicolons
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"Proteus syndrome is caused by sporadic mosaic mutations of a serine/threonine protein kinase encoded by the AKT1 gene; non-mosaic mutations are lethal. This enzyme is essential for normal cell growth hormone response. The genetic basis of the condition was elucidated in 2011 7,8."

Line 53:130 · Use semicolons judiciously.
Biographical Lifespan
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"History and etymology"

Line 58:1 · A bold element in the History and etymology section should be a person; it would be useful to have their lifespan details: '<h4>History and etymology</h4> <p>The name of this syndrome comes from the Greek god of the sea Proteus who had the ability to change his shape to avoid capture, it was proposed by Wiedemann et al. in 1983. The name thus refers to the unpredictable asymmetric gigantism/hemihypertrophy associated with this disease. The first case report (1884) of this disease is credited to <strong>Sir Frederick Treves</strong> '