"The demographics of patients affected by radiation-induced heart disease are those of the underlying condition for which radiation therapy was performed. Within this population, radiation-induced heart disease is estimated between 10-30%, most commonly occurring in a period of 5-10 years after the treatment completion date; however, importantly, many manifestations can occur acutely as well 8,9,11."
"The demographics of patients affected by radiation-induced heart disease are those of the underlying condition for which radiation therapy was performed. Within this population, radiation-induced heart disease is estimated between 10-30%, most commonly occurring in a period of 5-10 years after the treatment completion date; however, importantly, many manifestations can occur acutely as well 8,9,11."
"In radiation-induced heart disease, radiographic appearances vary considerably depending on the part of the heart involved 1,2,4,6. Although plain radiographs, echocardiography, and CT are useful modalities, cardiac MRI is considered to be the best modality for evaluating radiation-induced heart disease 1,2,4,6. The role of imaging is to provide a diagnosis and assess severity 1,2,4,6."
"a variety of imaging modalities may be employed to assess coronary arteries and associated functional and perfusion defects in these patients, such as stress echocardiography, nuclear myocardial perfusion imaging, CT calcium scoring, CT coronary angiography (see cardiac CT), and coronary angiography 1,2,4,6,9,11"
"however, cardiac MRI is the optimal imaging modality for assessing cardiac function, cardiac tissue characterisation and distinguishing it from other restrictive cardiomyopathies 1,2,4,6,11"
"The demographics of patients affected by radiation-induced heart disease are those of the underlying condition for which radiation therapy was performed. Within this population, radiation-induced heart disease is estimated between 10-30%, most commonly occurring in a period of 5-10 years after the treatment completion date; however, importantly, many manifestations can occur acutely as well 8,9,11."
"arrhythmias occur due to the aforementioned myocardial fibrosis in regions critical to the conduction system; these are most commonly not clinically significant 1-5"
"management depends on the severity of the valvulopathy; valve surgery or replacement (e.g. transcatheter aortic valve implantation) may eventually be necessary 1,4,9,10"
"often no treatment is needed; however, anti-arrhythmic medications may be used 1,4,9"
"prior or concurrent chemotherapy, especially with anthracyclines (e.g. doxorubicin)"
"lack of cardiac protection (e.g. subcarinal blocking)"
"this typically involves echocardiography, but can include other non-invasive modalities (e.g. cardiac MRI, cardiac CT)"
"this typically involves echocardiography, but can include other non-invasive modalities (e.g. cardiac MRI, cardiac CT)"