"It was first described by the American pathologist, Maurice N Richter (1897-1988) in 1928, who worked at New York University Medical Centre 4,11."
"It has been expanded to include other lymphoid malignancies that develop in CLL patients, including Hodgkin disease, prolymphocytic leukaemia (T-PLL), the Hodgkin variant of Richter transformation, small non-cleaved cell lymphoma, lymphoblastic lymphoma, and hairy cell leukaemia 8. Lymph node biopsy is required for the diagnosis of Richter transformation."
"It has been expanded to include other lymphoid malignancies that develop in CLL patients, including Hodgkin disease, prolymphocytic leukaemia (T-PLL), the Hodgkin variant of Richter transformation, small non-cleaved cell lymphoma, lymphoblastic lymphoma, and hairy cell leukaemia 8. Lymph node biopsy is required for the diagnosis of Richter transformation."
"Extranodal involvement is rare and can involve the gastrointestinal tract, central nervous system, skin, eye, lung, kidney, or testis."