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Lint: striatocapsular-infarct

Strong
warning

"Thus, while striatocapsular infarcts occur in a similar area to lacunar infarcts, and have previously been described as giant lacunes or super lacunes 1, they are not only larger than Miller Fisher’s lacune definition 5 but also have a different pathogenesis and clinical phenotype 1-4."

Line 5:124 · Generally, don't use bold in text: '<strong>giant lacunes</strong>'

"Thus, while striatocapsular infarcts occur in a similar area to lacunar infarcts, and have previously been described as giant lacunes or super lacunes 1, they are not only larger than Miller Fisher’s lacune definition 5 but also have a different pathogenesis and clinical phenotype 1-4."

Line 5:158 · Generally, don't use bold in text: '<strong>super lacunes</strong>'

"Furthermore, Distinguishing striatocapsular infarcts from lenticulostriate infarcts is important even though the terminology is used inconsistently in the literature given that it points to a different pathophysiology. As such the term large lenticulostriate infarct that is sometimes used should probably be avoided."

Line 6:240 · Generally, don't use bold in text: '<strong>large lenticulostriate infarct</strong>'
EG List And
warning

"Although there is a variable clinical presentation, classically patients with striatocapsular infarcts, in the acute phase, exhibit both cortical (e.g. aphasia, sensory neglect or extinction, apraxia) and subcortical (e.g. upper limb hemiparesis, dysarthria) neurological signs, despite the cortex not being directly involved in the infarction 1-4. The underlying mechanisms for these cortical signs being present in this subcortical striatocapsular infarction are unfortunately not well understood, but are thought to be due to decreased, but not absent, cortical blood flow, as discussed below 1-4."

Line 13:151 · An e.g. list gives selected examples, so it should not end with 'and' or 'or': 'e.g. aphasia, sensory neglect or'.
Commas
suggestion

"Although there is a variable clinical presentation, classically patients with striatocapsular infarcts, in the acute phase, exhibit both cortical (e.g. aphasia, sensory neglect or extinction, apraxia) and subcortical (e.g. upper limb hemiparesis, dysarthria) neurological signs, despite the cortex not being directly involved in the infarction 1-4. The underlying mechanisms for these cortical signs being present in this subcortical striatocapsular infarction are unfortunately not well understood, but are thought to be due to decreased, but not absent, cortical blood flow, as discussed below 1-4."

Line 13:54 · More than 5 commas in a single sentence might make it more difficult to read.