"Epidemiology "
"chronic relapsing–remitting pattern"
"T2/FLAIR: high signal of affected regions in the early stages 3,15"
"DWI/ADC: restricted diffusion may be seen in early stages 15,16"
"T1 C+ (Gd): enhancement of affected regions may occur in the early stages 15"
"decreased NAA: from neuronal loss in early stages"
Expected headings
"Epidemiology "
"Major criteria"
"Minor criteria"
"Signal characteristics"
"Subacute sclerosing panencephalitis (SSPE), also known as Dawson disease, is a rare, chronic, progressive, and almost universally fatal encephalitis that primarily affects children and young adults, caused by a persistent infection from an immune-resistant measles virus."
"Clinical presentation is gradual, progressive neuropsychological deterioration, consisting of personality change, seizures, myoclonus, ataxia, photosensitivity, ocular abnormalities, spasticity, and coma."
"Subacute sclerosing panencephalitis develops in 4-11 in 100,000 people infected with measles, although this is increased in patients who contract measles at"
"Histopathologically, subacute sclerosing panencephalitis demonstrates similar changes to those seen in other chronic viral cerebral infections 2. There are some characteristic histopathological features, including astrocytic intranuclear granulofilamentous inclusions and nucleocapsids within oligodendrocytes 15. There is relative sparing of the cerebellum 15."
"Histopathologically, subacute sclerosing panencephalitis demonstrates similar changes to those seen in other chronic viral cerebral infections 2. There are some characteristic histopathological features, including astrocytic intranuclear granulofilamentous inclusions and nucleocapsids within oligodendrocytes 15. There is relative sparing of the cerebellum 15."
"Gradually, more extensive white matter involvement develops with additional involvement of the corpus callosum and basal ganglia 1,15. The putamen is the most commonly involved basal ganglion, followed by the globus pallidus and caudate nucleus. The thalamus is rarely involved 9. There is also variable involvement of the brainstem, the corona radiata, and the cerebellar peduncles 8 ."
"Subacute sclerosing panencephalitis develops in 4-11 in 100,000 people infected with measles, although this is increased in patients who contract measles at"