"Complications include global cerebral atrophy, subacute combined degeneration of the cord due to vitamin B12 deficiency, Wernicke encephalopathy due to thiamine (vitamin B1) deficiency and alterations in the 5-HT system (observed on fMRI). For more information on CNS complications, please refer to the article anorexia nervosa (CNS)."
Expected headings
"Central nervous system"
"Cardiac"
"Gastrointestinal"
"Musculoskeletal"
"Respiratory"
"Head and neck"
"low body weight relative to age, sex and health"
"Patients are more likely to be osteopenic due to low body mass, lack of vitamin D, calcium and oestrogen. Patients tend to have a shorter stature and multiple vertebral and extraspinal fractures with minimal stress."
"There are reports of patients having diaphragmatic dysfunction, aspiration pneumonia 10, early-onset emphysema (due to autophagy) and recurrent pulmonary infections (due to poor immune function) 7,8,11."