"T1: hypointense to muscle"
"T1 C+: enhances"
"T2: hypointense to muscle"
"Pan-TRK"
"Pan-TRK"
"Confirming the presence of PAX3 rearrangement is helpful in establishing the diagnosis 5."
Expected headings
"Histology"
"Immunohistochemistry"
"Biphenotypic sinonasal sarcomas are characterised by rearrangements of PAX3, a transcription factor responsible for skeletal muscle and neural crest differentiation 1,5. A number of genetic abnormalities have been identified in these tumours, including PAX3-MAML3 fusion protein (t(2;4)(q35;q31.1) - most common; PAX3-NCOA1 fusion; PAX3-FOXO1 fusion; and as yet to be elucidated abnormalities referred to as PAX3-X 1,3."
"Biphenotypic sinonasal sarcomas are characterised by rearrangements of PAX3, a transcription factor responsible for skeletal muscle and neural crest differentiation 1,5. A number of genetic abnormalities have been identified in these tumours, including PAX3-MAML3 fusion protein (t(2;4)(q35;q31.1) - most common; PAX3-NCOA1 fusion; PAX3-FOXO1 fusion; and as yet to be elucidated abnormalities referred to as PAX3-X 1,3."
"Biphenotypic sinonasal sarcomas are characterised by rearrangements of PAX3, a transcription factor responsible for skeletal muscle and neural crest differentiation 1,5. A number of genetic abnormalities have been identified in these tumours, including PAX3-MAML3 fusion protein (t(2;4)(q35;q31.1) - most common; PAX3-NCOA1 fusion; PAX3-FOXO1 fusion; and as yet to be elucidated abnormalities referred to as PAX3-X 1,3."