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Lint: brush-sign

Strong
warning

"cortical veins: sometimes referred to as the cortical vessel sign 1,3-6"

Line 4:53 · Generally, don't use bold in text: '<strong>cortical vessel sign </strong>'

"subependymal and medullary veins: sometimes referred to as the brush sign 1,3-6, although not exclusively in the context of ischaemic stroke as this same sign is also used in the context of moyamoya disease, cerebral venous sinus thrombosis, and cerebral venous air embolism 7-9"

Line 5:71 · Generally, don't use bold in text: '<strong>brush sign</strong>'
Semicolons
suggestion

"a positive prominent vessel sign may be associated with a cardioembolic aetiology of ischaemic stroke, whereby it is postulated that collaterals have not had time to develop; this contrasts with ischaemic stroke caused by long-standing steno-occlusive arterial disease whereby there is more time for collaterals to develop 1,4"

Line 10:195 · Use semicolons judiciously.