"reversible opening of the blood-brain-barrier to improve the delivery of drugs, gene therapy and even stem cells into target areas within the brain 11-14 (pre-clinical research)"
"essential tremor 3,4 (FDA and international approval); the primary target is the ventral intermediate nucleus (ViM) of the thalamus"
"Parkinson disease 5,23 (FDA and international approval); the ventral intermediate nucleus (ViM) of the thalamus is targeted for tremor, the globus pallidus or subthalamic nucleus are targeted for motor fluctuations, and the pallidothalamic tract is targeted for multiple symptoms"
"depression 6 (International approval but not FDA approved)"
"obsessive-compulsive disorder (OCD) 7 (international approval but not FDA approved)"
"chronic neuropathic pain 8 (international approval but not FDA approved)"
"HIFU is also being used and trialed for the treatment of extracranial pathology such as uterine fibroids (approved by FDA), breast cancer (cleared for use in multiple countries but not yet approved in the United States of America), and prostate cancer (cleared for use in multiple countries including the United States of America) 15-21."
"Deep brain ultrasound (DBUS) therapy, also known as transcranial MR-guided focused ultrasound (MRgFUS), is a form of precision medicine using a technique based on the principle of high-intensity focused ultrasound (HIFU), also referred to as focused ultrasound surgery (FUS)."
"essential tremor 3,4 (FDA and international approval); the primary target is the ventral intermediate nucleus (ViM) of the thalamus"
"Parkinson disease 5,23 (FDA and international approval); the ventral intermediate nucleus (ViM) of the thalamus is targeted for tremor, the globus pallidus or subthalamic nucleus are targeted for motor fluctuations, and the pallidothalamic tract is targeted for multiple symptoms"