"T1: hypointense 2"
"T2: hyperintense with apparently preserved cortical striations 1"
"DWI: similar to normal cortex"
"FDG-PET: increased uptake"
"Tl-201 SPECT: increased uptake"
"It is named after the French neurologist and neuropsychiatrist Jacques Jean Lhermitte (1877-1959), with his physician colleague P Duclos, who jointly described the condition in 1920 6."
"loss of PTEN protein expression (Cowden syndrome/COLD syndrome)"
"slightly reduced NAA (by about 10%) 1,2"
"The appearance may be mimicked by extensively nodular medulloblastoma (SHH molecular subgroup)."
"reduced myo-inositol (by 30-80%)"
"Tl-201 SPECT: increased uptake"
Expected headings
"Associations"
"Derangement of the normal laminar cellular organisation of the cerebellum is present. There is thickening of the outer molecular cell layer, loss of the middle Purkinje cell layer, and infiltration of the inner granular cell layer with dysplastic ganglion cells of various sizes 6."
"The dysplastic mass grows very slowly, and initial treatment revolves around treating hydrocephalus. Surgical resection is often curative, with only a few case reports of recurrence 3. Importantly it is crucial to remember the association with Cowden syndrome, hence, increased risk of other neoplasms such as breast, endometrial and thyroid cancers. Therefore, a recommendation for further imaging or clinical assessment of possible tumours in these locations should be included in the radiologist's report."