"Gluten ataxia is a relatively common central nervous system manifestation of coeliac disease and is usually encountered in individuals who do not have overt gastrointestinal symptoms."
"Gastrointestinal symptoms are usually absent, found in only 10% of individuals, and on duodenal biopsy, a diagnosis of coeliac disease can be made in on half of patients 2. As such, the diagnosis of gluten ataxia requires screening for antibodies associated with coeliac disease: anti-gliadin, anti-EMA, anti-TG2, and anti-TG6 antibodies 2."
"There is some evidence that gluten-dependent transglutaminase 6 (TG6) autoantibodies (IgA or IgG) react against cells within the cerebellum 1."
"Treatment is primarily with strict adherence to a gluten-free diet. In many individuals, objective and subjective improvement in ataxia can be demonstrated 2."