"Although patients with Kallmann syndrome are anosmic from birth, this usually is not apparent to either the parents or the child. The diagnosis is only made when puberty does not occur. At that time gonadotropin levels (FSH and LH) and sex hormones (testosterone and oestradiol) are low, whereas other pituitary hormones are normal 3."
"Kallmann syndrome is a genetic condition with multiple implicated genes 4. The most common of these is the ANOS1 (formerly KAL1) gene, which is inherited in an X-linked recessive pattern; however, there are other genes that may be inherited in autosomal patterns 4. It is thought that mutation of this gene, and other similar genes, results in failure of appropriate migration of gonadotropin-releasing hormone-secreting cells and olfactory neurones during embryogenesis 4."
"midline defects (e.g. cleft lip and palate)"
"Kallmann syndrome is a genetic condition with multiple implicated genes 4. The most common of these is the ANOS1 (formerly KAL1) gene, which is inherited in an X-linked recessive pattern; however, there are other genes that may be inherited in autosomal patterns 4. It is thought that mutation of this gene, and other similar genes, results in failure of appropriate migration of gonadotropin-releasing hormone-secreting cells and olfactory neurones during embryogenesis 4."
"History and etymology"