"Besides large cells, neuroendocrine carcinomas are usually characterised by a Ki67 index >50% 1,2. Other potentially positive expressions include CD57 P504S and PSMA 2,3."
"There are case descriptions of large cell neuroendocrine tumours showing uptake of FDG, PSMA and/or somatostatin receptor positivity 7."
Expected headings
"Radiographic features"
"MRI"
"Nuclear medicine"
"Immunohistochemistry stains are usually positive for at least one neuroendocrine marker as synaptophysin, CD56 or chromogranin A. It is usually only focally positive or negative for prostate-specific antigen (PSA) 1-5."
"form, location and size"
"There are case descriptions of large cell neuroendocrine tumours showing uptake of FDG, PSMA and/or somatostatin receptor positivity 7."