"CT is the method of choice and may show nodules not seen on chest X-rays due to pleural effusion. The pleural metastases usually manifest as enhancing nodular or lenticular masses. Other findings seen on CT are enlarged mediastinal lymph nodes, lung nodules, rib lesions, or subcutaneous extension."
"The infiltration of the pleura usually manifests as pleural effusion, which is the first manifestation of pleural metastasis. In addition to the symptoms and systemic manifestations of neoplastic disease, as in general conditions, anorexia or weight loss, one of the most constant symptoms is dyspnoea, which occurs >50% of patients with malignant pleural effusion."
"It can be difficult to differentiate pleural metastasis from primary pleural malignancy such as malignant mesothelioma since both can cause pleural effusions, pleural nodules, and isolated, diffuse or nodular thickening."