"Pseudomonas aeruginosa"
"Staphylococcus aureus: especially in the first 6 months of life 1"
"Haemophilus influenzae: especially in the first 6 months of life"
"Burkholderia cepacia"
"may co-exist with CF in 5-10% of patients 3 (with serum precipitins against Aspergillus fumigatus detected ~50% of patients)"
"Pseudomonas aeruginosa"
"Staphylococcus aureus: especially in the first 6 months of life 1"
"Haemophilus influenzae: especially in the first 6 months of life"
"Burkholderia cepacia"
"Brasfield scoring system: can be used to score disease severity on plain film"
"Chrispin-Norman score: is used to provide a summative assessment of structural lung changes in patients"
"Trikafta® (elexacaftor/tezacaftor/ivacaftor)"
"Symdeko® (tezacaftor/ivacaftor)"
"Orkambi® (lumacaftor/ivacaftor)"
"Kalydeco® (ivacaftor)"
"Langerhans cell histiocytosis (LCH)"
"Chrispin-Norman score: is used to provide a summative assessment of structural lung changes in patients"
Expected headings
"Scoring"
"HRCT"
"CT angiography (thorax)"
"Radiation exposure"
"In the lung, the cystic fibrosis transmembrane regulator (CFTR) is a protein responsible for efflux of chloride and inhibition of the sodium channel's activity which controls the influx of sodium. Therefore, under normal circumstances, salt and chloride remain in the lumen and keep water there osmotically. In CF patients, too little chloride is pumped out, too much sodium is reabsorbed resulting in osmotic re-absorption of water from the lumen. The result is iso-osmotic, but low volume, secretions, which tend to dry out, or be thick as they still contain all the other constituents."
"Other features to be sought include hyperinflation, regions of consolidation, lymph node enlargement, pneumothorax and pulmonary arterial hypertension."