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Lint: mediastinal-yolk-sac-tumour

mediastinal-yolk-sac-tumour
List Caps
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"Schiller-Duval bodies (might be absent)"

Line 19:4 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Acronyms
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"markedly elevated serum AFP"

Line 20:32 · 'AFP' has no definition. Spell it out if it's unfamiliar to the audience.

"coexpression of cytokeratins, SALL4, GPC3 and possibly AFP"

Line 21:60 · 'AFP' has no definition. Spell it out if it's unfamiliar to the audience.

"A large heterogeneous mediastinal mass with lung metastases on imaging in young men or children in the setting of rapid symptom onset and elevated serum AFP might indicate a non-seminomatous germ cell tumour."

Line 25:160 · 'AFP' has no definition. Spell it out if it's unfamiliar to the audience.

"Clinical signs and symptoms are frequently chest-related and include dyspnoea, chest pain and cough, systemic symptoms include weight loss, fever and haemoptysis 1-3. They might also present with superior vena cava syndrome or might be found incidentally on imaging studies 1. AFP is most commonly elevated 1. Β-hCG might be elevated 2."

Line 27:324 · 'AFP' has no definition. Spell it out if it's unfamiliar to the audience.

"Immunohistochemistry stains of mediastinal yolk sac tumours are usually positive for cytokeratins such as AE1 and/or AE3, GPC3 and SALL4 but usually do not express OCT4, SOX2 and D2-40 1. They variably express AFP, PLAP and KIT/CD117."

Line 60:225 · 'AFP' has no definition. Spell it out if it's unfamiliar to the audience.

"Immunohistochemistry stains of mediastinal yolk sac tumours are usually positive for cytokeratins such as AE1 and/or AE3, GPC3 and SALL4 but usually do not express OCT4, SOX2 and D2-40 1. They variably express AFP, PLAP and KIT/CD117."

Line 60:230 · 'PLAP' has no definition. Spell it out if it's unfamiliar to the audience.

"Immunohistochemistry stains of mediastinal yolk sac tumours are usually positive for cytokeratins such as AE1 and/or AE3, GPC3 and SALL4 but usually do not express OCT4, SOX2 and D2-40 1. They variably express AFP, PLAP and KIT/CD117."

Line 60:239 · 'KIT' has no definition. Spell it out if it's unfamiliar to the audience.
Colons
warning

"endodermal sinus/pseudopapillary: Schiller-Duval bodies resembling primitive glomeruli"

Line 51:37 · The first word after a colon should almost always be lowercase. In this case, it's not: ': Schiller-Duval bodies'.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Pathogenesis"

Line 39:1 · "Pathogenesis" is not a recognised heading for this article type.
Oxford Comma
suggestion

"various histological patterns representing the yolk sac, allantois and extraembryonic mesenchyme"

Line 13:60 · Use the Oxford comma in 'sac, allantois and extraembryonic'.

"coexpression of cytokeratins, SALL4, GPC3 and possibly AFP"

Line 21:35 · Use the Oxford comma in 'SALL4, GPC3 and possibly'.

"Clinical signs and symptoms are frequently chest-related and include dyspnoea, chest pain and cough, systemic symptoms include weight loss, fever and haemoptysis 1-3. They might also present with superior vena cava syndrome or might be found incidentally on imaging studies 1. AFP is most commonly elevated 1. Β-hCG might be elevated 2."

Line 27:141 · Use the Oxford comma in 'loss, fever and haemoptysis'.

"microcystic/reticular: cystic spaces lined by cuboidal, flat or columnar epithelium"

Line 48:51 · Use the Oxford comma in 'cuboidal, flat or columnar'.

"Immunohistochemistry stains of mediastinal yolk sac tumours are usually positive for cytokeratins such as AE1 and/or AE3, GPC3 and SALL4 but usually do not express OCT4, SOX2 and D2-40 1. They variably express AFP, PLAP and KIT/CD117."

Line 60:121 · Use the Oxford comma in 'AE3, GPC3 and SALL4'.

"Immunohistochemistry stains of mediastinal yolk sac tumours are usually positive for cytokeratins such as AE1 and/or AE3, GPC3 and SALL4 but usually do not express OCT4, SOX2 and D2-40 1. They variably express AFP, PLAP and KIT/CD117."

Line 60:168 · Use the Oxford comma in 'OCT4, SOX2 and D2'.

"Immunohistochemistry stains of mediastinal yolk sac tumours are usually positive for cytokeratins such as AE1 and/or AE3, GPC3 and SALL4 but usually do not express OCT4, SOX2 and D2-40 1. They variably express AFP, PLAP and KIT/CD117."

Line 60:225 · Use the Oxford comma in 'AFP, PLAP and KIT'.
Inline EG
suggestion

"associated complications (e.g. superior vena cava obstruction)"

Line 73:30 · Consider replacing a bracketed e.g. with an inline e.g. after a comma.
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