"T1: highly variable and can be hypointense to isointense"
"DWI: often shows restricted diffusion"
"elevated taurine (Tau) peak (relatively specific for PNET) 8-9"
"Primitive neuroectodermal tumours (or CNS PNET) were considered aggressive neoplasms of the brain, most frequently encountered in the paediatric population. Importantly, the term no longer appears in the WHO classification of CNS tumours 11,12."
"Traditionally a number of tumours variably fell under the umbrella term CNS PNET 7:"
"supratentorial PNET: 15% of all CNS PNET"
"supratentorial PNET: 15% of all CNS PNET"
"pineoblastoma: most common supratentorial PNET (discussed separately)"
"spinal PNET: rare"
"Additionally, a primitive neuronal component can also be identified in glioblastomas, previously referred to as glioblastoma with PNET-like component but now simply recognised as a histological pattern 10,11."
"decreased NAA 9"
"elevated taurine (Tau) peak (relatively specific for PNET) 8-9"
"atypical teratoid/rhabdoid tumour (AT/RT)"
"atypical teratoid/rhabdoid tumour (AT/RT)"
"The remainder of this article focuses on what has historically been denoted as supratentorial primitive neuroectodermal tumour (sPNET). "
"typically iso to hyper-attenuating on non-contrast imaging 7"
Expected headings
"Associations"
"They typically occur in the paediatric population, usually during the first 10 years of life, with a mean age of 5 years 7. There is a recognised male predilection."
"Clinical presentation is non-specific and cannot be distinguished from other aggressive intracranial masses. Symptoms of raised intracranial pressure, seizures and focal neurology may be present."