"Prostate-specific membrane antigen (PSMA), also known as glutamate carboxypeptidase II, is a type II transmembrane glycoprotein that has become an increasingly prominent imaging biomarker 1. PSMA has emerged as a useful target in PET imaging of prostate cancer, especially in the evaluation of small volume lymph node and bone metastases using tracers like Ga-68 PSMA (the first radiotracer to be approved by the FDA in December 2020) and F-18 PSMA 2,11. The theranostic agent Lutetium-177 vipivotide tetraxetan (trade name Pluvicto) used to treat metastatic castration-resistant prostate cancer obtained FDA approval in 2022 12."
"Prostate-specific membrane antigen (PSMA), also known as glutamate carboxypeptidase II, is a type II transmembrane glycoprotein that has become an increasingly prominent imaging biomarker 1. PSMA has emerged as a useful target in PET imaging of prostate cancer, especially in the evaluation of small volume lymph node and bone metastases using tracers like Ga-68 PSMA (the first radiotracer to be approved by the FDA in December 2020) and F-18 PSMA 2,11. The theranostic agent Lutetium-177 vipivotide tetraxetan (trade name Pluvicto) used to treat metastatic castration-resistant prostate cancer obtained FDA approval in 2022 12."
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