"open: (80-90%) especially if detected antenatally 4"
"closed: if covering skin present"
"maternal alpha fetoprotein (MSAFP): elevated in 80% of open spina bifida (and normal in most fetuses with closed spina bifida) 15."
"Chiari 2 malformation"
"Notably, closed and skin covered spinal lesions typically do not have any associated cranial abnormality. A normal cranial ultrasound therefore does not exclude a neural tube defect."
Expected headings
"Associations"
"Complications"
"There are many ways of classifying a spina bifida. One method is according to the extent of the defect and is as:"
"Notably, closed and skin covered spinal lesions typically do not have any associated cranial abnormality. A normal cranial ultrasound therefore does not exclude a neural tube defect."