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Lint: central-atypical-cartilaginous-tumourlow-grade-chondrosarcoma-1

Citation Punctuation Sup
error

"A provisional diagnosis can often be made by a combination of clinical examination and imaging, especially MRI 2,7,8, as well as histology 1-3, should there be a doubt after advanced imaging with the collaboration of a multidisciplinary team 2."

Line 8:122 · Punctuation after citations should never be superscripted. '<sup>2,7,8, </sup>'
Headings Spacing
error

"Location "

Line 25:1 · Never put spaces at either end of headings.
Strong List Colon Position
error

"T1: low to intermediate signal (iso- to slightly hyperintense vs muscle)"

Line 108:8 · When enboldening an intro, the colon should not be bold. '<strong>T1:</strong> low'

"T2: high intensity in non-mineralised/calcified portions with or without signal voids"

Line 109:8 · When enboldening an intro, the colon should not be bold. '<strong>T2:</strong> high'

"GRE/SWI: blooming of mineralised/calcified portions"

Line 110:8 · When enboldening an intro, the colon should not be bold. '<strong>GRE/SWI:</strong> blooming'

"T1 C+ (Gd): heterogeneous moderate to intense contrast enhancement"

Line 111:8 · When enboldening an intro, the colon should not be bold. '<strong>T1 C+ (Gd): </strong>heterogeneous'

"DCE: arterial enhancement within 10s has been reported to favour chondrosarcoma vs enchondroma 11, though specificity is limited"

Line 112:8 · When enboldening an intro, the colon should not be bold. '<strong>DCE:</strong> arterial'
Units
error

"DCE: arterial enhancement within 10s has been reported to favour chondrosarcoma vs enchondroma 11, though specificity is limited"

Line 112:58 · Put a space between the number and the unit in '10s'.
En Dash
error

"contrast enhancement pattern (DCE arterial enhancement)"

Line 124:42 · Use a hyphen-minus ('-') instead of an en-dash ('–').
Adjectival Hyphens
error

"Pre-operative histology carries the risk of tumour seeding within the biopsy tract 6,7,11."

Line 140:4 · Only use medical adjectival hyphens where the letters at the end and start of the compound word are the same, e.g. post-transplant. In this case, don't use the hyphen: 'Pre-operative'.
Strong
warning

"The terminology depends mainly on localisation. Low-grade tumours arising from the long and short tubular bones of the extremities should be termed ‘central atypical cartilaginous tumours’, whereas tumours arising from the axial skeleton, including the flat bones of the pelvis, scapula and skull base, are called chondrosarcoma grade 1 1-4."

Line 3:4 · Generally, don't use bold in text: 'The terminology depends mainly on localisation. Low-grade tumours arising from the long and short tubular bones of the extremities should be termed ‘central atypical cartilaginous tumours’,<strong> </strong>whereas tumours arising from the axial skeleton, including the flat bones of the pelvis, scapula and skull base, are called chondrosarcoma grade 1'
Emphasis
warning

"Individuals with enchondromatosis and a somatic mosaic mutation in IDH1 or IDH2 have a high risk of developing atypical cartilaginous tumours/chondrosarcomas grade 1, especially those with enchondromas in the pelvis or multiple enchondromas in both small and long or flat bones (~46%) 1,10. The risk in patients with multiple enchondromas confined to the hands and feet is substantially lower (~15%) 1,10."

Line 24:71 · Italics should be used only in exceptional circumstances: '<em>IDH1</em> or <em>IDH2</em>'

"About 50% of primary and 75-80% of secondary low-grade chondrosarcomas display somatic mutations in the IDH1 and IDH2 genes 1,3."

Line 62:108 · Italics should be used only in exceptional circumstances: '<em>IDH1</em>'
Headings Valid
warning

Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Location "

Line 25:1 · "Location " is not a recognised heading for this article type.

"Associations"

Line 63:1 · "Associations" is under the wrong parent heading (found under "Pathology").

"Plain radiograph/CT"

Line 73:1 · "Plain radiograph/CT" is not a recognised heading for this article type.

"Signal characteristics"

Line 106:1 · "Signal characteristics" is not a recognised heading for this article type.

"Complications"

Line 138:1 · "Complications" is under the wrong parent heading (found under "Treatment and prognosis").
Oxford Comma
suggestion

"The terminology depends mainly on localisation. Low-grade tumours arising from the long and short tubular bones of the extremities should be termed ‘central atypical cartilaginous tumours’, whereas tumours arising from the axial skeleton, including the flat bones of the pelvis, scapula and skull base, are called chondrosarcoma grade 1 1-4."

Line 3:292 · Use the Oxford comma in 'pelvis, scapula and skull'.

"MRI is an important tool in the detection, grading and differentiation of low-grade chondrosarcoma versus enchondroma and intermediate to higher-grade chondrosarcoma, as well as to other bone tumours."

Line 84:36 · Use the Oxford comma in 'detection, grading and differentiation'.
Semicolons
suggestion

"Central atypical cartilaginous tumours/chondrosarcomas grade 1 (ACT/CS1) are aggressive cartilage matrix-forming tumours evolving from endochondral ossification 1,3. Primary lesions develop without precursor lesions; secondary lesions arise from a pre-existing benign precursor lesion, such as an enchondroma 1."

Line 22:237 · Use semicolons judiciously.
Biographical Lifespan
suggestion

"History and etymology"

Line 141:1 · A bold element in the History and etymology section should be a person; it would be useful to have their lifespan details: '<h4>History and etymology</h4> <p>Chondrosarcomas were first described by the American bone pathologists <strong>Louis Lichtenstein</strong> '