"O/E LHR 15-25% (severe pulmonary hypoplasia): predicted survival ≈ 15%"
"Bochdalek hernia"
"Morgagni hernia"
"O/E LHR"
"O/E LHR 15-25% (severe pulmonary hypoplasia): predicted survival ≈ 15%"
"O/E LHR 26-45% (moderate pulmonary hypoplasia): predicted survival 30-75%"
"O/E LHR >45% (mild pulmonary hypoplasia): very likely to survive"
"mnemonic: BBBBB"
"T2 weighted half-fourier acquisition single-shot turbo spin echo (HASTE) "
"MRI allows the measurement of fetal lung volumes which provide an estimate of the severity of pulmonary hypoplasia. The total fetal lung volume (TFLV) can be calculated from a contiguous T2-weighted HASTE sequence and an observed-to-expected TFLV (O/E TFLV) derived. It has been found to predict well both mortality and morbidity, including the need for ECMO and the development of bronchopulmonary dysplasia 14,15."
"MRI allows the measurement of fetal lung volumes which provide an estimate of the severity of pulmonary hypoplasia. The total fetal lung volume (TFLV) can be calculated from a contiguous T2-weighted HASTE sequence and an observed-to-expected TFLV (O/E TFLV) derived. It has been found to predict well both mortality and morbidity, including the need for ECMO and the development of bronchopulmonary dysplasia 14,15."
"Large CDH have a poor prognosis, due to pulmonary hypoplasia and perinatal mortality may be as high as 80%. Successful management is dependent on specialist paediatric facilities, with the ability to offer surgery, ECMO etc."
"A composite prognostic index (CDH-CPI) comprising 10 prenatal parameters has been developed and was found to have a stronger correlation with survival and need for ECMO than any one parameter individually 16."
"cardiac dysfunction: RV, LV or combined"
"Lung-head ratio: can be assessed on both ultrasound or MRI; MRI measured LHR has been found to have a slightly higher prognostic accuracy than with ultrasound 5."
"intra-thoracic liver"
Expected headings
"Types"
"Associations"
"Complications"
"intrathoracic herniation of the liver; noted in up to 85% of cases and is associated with a worse prognosis"
"Lung-head ratio: can be assessed on both ultrasound or MRI; MRI measured LHR has been found to have a slightly higher prognostic accuracy than with ultrasound 5."
"lungs appear hyperintense (composed primarily of water) while heart, mediastinum and liver appear hypointense"
"cardiac dysfunction: RV, LV or combined"