"COL4A1 brain small-vessel disease"
"multisystemic smooth muscle dysfunction syndrome (ACTA2 cerebral arteriopathy)"
"COL4A1 brain small-vessel disease"
"HANAC syndrome (hereditary angiopathy with nephropathy, aneurysms, and muscle cramps syndrome)"
"The 2026 AHA guideline introduces, for the first time, formal recommendations for children with ischaemic stroke 8:"
"prothrombin 20210 mutation 5"
Expected headings
"Ischaemic stroke"
"Haemorrhagic stroke"
"Venous thrombosis"
"CNS vasculitis (e.g. large vessel childhood primary angiitis of the CNS (cPACNS), systemic lupus erythematosus, etc.)"
"other genetic disorders (e.g. neurofibromatosis type 1 2)"
"CNS vasculitis (e.g. large vessel childhood primary angiitis of the CNS (cPACNS), systemic lupus erythematosus, etc.)"
"skull base/intracranial or other proximal venous infection (e.g. Lemierre syndrome)"
"malignancy (e.g. acute lymphoblastic leukaemia)"
"chemotherapy (e.g. L-asparaginase)"
"In paediatric patients with suspected stroke, brain and vascular MRI/MRA of the cervical and intracranial vessels is the preferred first-line imaging modality, given the importance of excluding arteriopathy, dissection, and non-ischaemic mimics. If MRI/MRA is not immediately available (within 25 minutes), CT/CTA of the head and neck is a reasonable alternative 8."
"thrombolysis: alteplase may be considered in children aged 28 days to 18 years presenting within 4.5 hours with disabling deficits; safety data are supportive, though efficacy remains uncertain 8"