"T1 C+ (Gd): can show leptomeningeal enhancement and pachymeningeal enhancement"
"FLAIR C+ (Gd): high signal in subarachnoid space 12"
"T1: low signal"
"T2/FLAIR: high signal"
"T1 C+ (Gd): variable, ranging from no enhancement 5 to peripheral nodular enhancement 9"
"DWI/ADC: variable, may have both facilitated or restricted diffusion 12,13"
"T1: low to intermediate (from mucin) signal 9"
"T2: high signal"
"FLAIR: variable signal ranging from full suppression to persistent high signal"
"CNS cryptococcosis results from infection of the central nervous system with the yeast-like fungus Cryptococcus neoformans, or less commonly, Cryptococcus gattii. It is the most common fungal infection and second most common opportunistic infection of the central nervous system."
Expected headings
"Meningeal disease"
"Cryptococcomas"
"Dilated perivascular spaces"
"Complications"
"Patients with cerebral cryptococcosis can present subtly and in a subacute fashion. Signs and symptoms may not be typical of pyogenic forms of meningitis/meningoencephalitis, but can include headache (most common symptom), seizures, altered mental state, focal neurological deficits, or visual loss due to raised intracranial pressure (causing papilloedema) 12,16."
"There are three dominant CNS forms to the disease depending on which part of the brain is affected:"
"variable; may have both facilitated or restricted diffusion 12,13"
"residual neurological deficits (e.g. visual or hearing impairment, focal deficits from lacunar ischaemic stroke)"
"specific complications relating to antifungal agents (e.g. hepatotoxicity)"