"Unlike acute disseminated encephalomyelitis (ADEM), tumefactive demyelinating lesions are usually not post-infective. Additionally, although patients with multiple sclerosis can develop large tumefactive demyelinating plaques (which have very similar appearances - see tumefactive multiple sclerosis), patients who present with a solitary tumefactive demyelinating lesion infrequently go on to develop multiple sclerosis (MS) 3."
"Baló-like"
"Marburg variant of multiple sclerosis"
"the pattern can otherwise be indistinguishable from that of neoplasms (decreased NAA/Cr ratio, increased Cho/Cr ratio, and variable lactate and lipid peaks)"
"high-grade glioma (e.g. GBM)"
Expected headings
"Signal characteristics"
"Video"
"Patients present with symptoms atypical for multiple sclerosis, such as focal neurologic deficits, seizures, and/or aphasia 5. Most do not progress to multiple sclerosis 6. In some instances, patients can deteriorate rapidly and succumb to illness (e.g. acute malignant Marburg variant of MS)."
"high-grade glioma (e.g. GBM)"
"tumefactive demyelination is not necessarily benign, and patients can have a fulminant course ending in demise (e.g. Marburg variant of MS)"
"inflammatory: multiple sclerosis (and variants, including acute malignant Marburg variant of MS, Schilder type of MS, Baló concentric sclerosis), systemic lupus erythematosus, neurosarcoidosis, Sjögren disease, neuro-Behçet disease, neuromyelitis optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), acute disseminated encephalomyelitis (ADEM) 12,14"
"inflammatory: multiple sclerosis (and variants, including acute malignant Marburg variant of MS, Schilder type of MS, Baló concentric sclerosis), systemic lupus erythematosus, neurosarcoidosis, Sjögren disease, neuro-Behçet disease, neuromyelitis optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), acute disseminated encephalomyelitis (ADEM) 12,14"