"total hemimegalencephaly: hemihypertrophy also involves the brainstem and cerebellum."
"In some cases, the affected cerebral hemisphere is involved only partially, and this has been termed "quadrantic dysplasia", "lobar hemimegalencephaly", or "hemi-hemimegalencephaly" by some authors 6."
"Hemimegalencephaly is a cryptogenic congenital disorder and does not have a recognised racial or gender predilection 3. It is rare, accounting for only ~0.2% of cases of childhood epilepsy 3."
"Klippel-Trenaunay Syndrome"
"Rasmussen encephalitis"
"total hemimegalencephaly: hemihypertrophy also involves the brainstem and cerebellum."
Expected headings
"Subtypes"
"It is a congenital malformation in which defective cellular organisation and neuronal migration result in hamartomatous overgrowth of a hemisphere. Macroscopically the affected hemisphere demonstrates, in addition to overgrowth, abnormal cortical development is present with areas of lissencephaly, agyria, pachygyria and polymicrogyria in varying proportions, with other areas appearing normal 3."
"All modalities able to image the brain (ultrasound, CT and MRI) will be able to more or less identify the key features, although MRI will give the best imaging. Typical features of the affected hemisphere include 1,4,5:"
"Treatment is targeted to the control of epilepsy, which can be difficult to manage medically. In refractory cases hemispherectomy is the treatment of choice and results in seizure control in at least 60% of cases when carefully selected; patients with contralateral malformations have a poorer surgical outcome 3."