"Immune thrombocytopenia (ITP), historically known as idiopathic thrombocytopenic purpura, is an autoimmune disorder characterised by a decrease in platelet numbers to"
"the definition of thrombocytopenia has been fixed at a platelet count of"
"previously the criteria was"
"platelet count usually"
"In most cases, the bleeding risk is inversely proportional to the platelet count 2. Curiously though, a significant minority of patients remain asymptomatic for years despite very low platelet counts. Greater than 50% cases with platelets of 30-50 × 109/L remain symptom-free 2."
"the abbreviation "ITP" was kept the same to facilitate consistency between the historic and new medical literature and to avoid confusion; historically, ITP stood for "idiopathic thrombocytopenic purpura", and now stands for immune thrombocytopenia"
"the abbreviation "ITP" was kept the same to facilitate consistency between the historic and new medical literature and to avoid confusion; historically, ITP stood for "idiopathic thrombocytopenic purpura", and now stands for immune thrombocytopenia"
"the abbreviation "ITP" was kept the same to facilitate consistency between the historic and new medical literature and to avoid confusion; historically, ITP stood for "idiopathic thrombocytopenic purpura", and now stands for immune thrombocytopenia"
"associated with systemic haemorrhage, e.g. GI bleeds"
"BTK inhibitors (e.g. rilzabrutinib)"
"Helicobacter pylori"
"splenectomy is associated with an elevated risk of infections by encapsulated micro-organisms, so vaccinations for pneumococcus, Haemophilus influenzae type B, and meningococcus are required"
"Helicobacter pylori"
"FcRn inhibitors (e.g. rozanolixizumab)"
"Syk inhibitors (e.g. fostamatinib)"
"cytotoxics are now less favoured than they were historically, e.g. cyclophosphamide, vinca alkaloids, and azathioprine"
Expected headings
"Primary"
"Secondary"
"Complications"
"the abbreviation "ITP" was kept the same to facilitate consistency between the historic and new medical literature and to avoid confusion; historically, ITP stood for "idiopathic thrombocytopenic purpura", and now stands for immune thrombocytopenia"
"corticosteroids (e.g. prednisolone)"
"FcRn inhibitors (e.g. rozanolixizumab)"
"thrombopoietin receptor agonists (e.g. romiplostim)"
"BTK inhibitors (e.g. rilzabrutinib)"
"Syk inhibitors (e.g. fostamatinib)"