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Lint: primary-sclerosing-cholangitis

Emphasis
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"genetics (HLA- DR2, DR3, B8) 20"

Line 5:22 · Italics should be used only in exceptional circumstances: '<em>HLA- DR2</em>, <em>DR3</em>, <em>B8</em>'
Acronyms
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"Most patients demonstrate at least one type of autoantibody, typically anti-smooth muscle antibody (ASMA) and antinuclear antibody (ANA), which are seen in up to 75%. p-ANCA is also positive in up to 80% of patients with primary sclerosing cholangitis 19."

Line 19:190 · 'ANCA' has no definition. Spell it out if it's unfamiliar to the audience.

"autoimmune hepatitis (AIH-PSC overlap)"

Line 33:37 · 'AIH-PSC' has no definition. Spell it out if it's unfamiliar to the audience.

"MRCP and ERCP"

Line 53:14 · 'ERCP' has no definition. Spell it out if it's unfamiliar to the audience.

"ERCP has traditionally been the gold standard for the depiction of the biliary tree, and also offers the ability to perform cholangioplasty, if necessary. In practice, however, MRCP is used before ERCP since it is non-invasive, can assess the liver, and avoids the 10% risk of hospitalisation from ERCP in primary sclerosing cholangitis patients 17."

Line 54:4 · 'ERCP' has no definition. Spell it out if it's unfamiliar to the audience.

"ERCP has traditionally been the gold standard for the depiction of the biliary tree, and also offers the ability to perform cholangioplasty, if necessary. In practice, however, MRCP is used before ERCP since it is non-invasive, can assess the liver, and avoids the 10% risk of hospitalisation from ERCP in primary sclerosing cholangitis patients 17."

Line 54:201 · 'ERCP' has no definition. Spell it out if it's unfamiliar to the audience.

"ERCP has traditionally been the gold standard for the depiction of the biliary tree, and also offers the ability to perform cholangioplasty, if necessary. In practice, however, MRCP is used before ERCP since it is non-invasive, can assess the liver, and avoids the 10% risk of hospitalisation from ERCP in primary sclerosing cholangitis patients 17."

Line 54:302 · 'ERCP' has no definition. Spell it out if it's unfamiliar to the audience.

"Cholangioplasty of dominant strictures is usually performed in a retrograde fashion via ERCP or via a transhepatic approach 6,7."

Line 78:92 · 'ERCP' has no definition. Spell it out if it's unfamiliar to the audience.
List Caps
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"Riedel thyroiditis"

Line 37:11 · In general, we don't start a list item with a capital letter. Exceptions are proper nouns.
Headings Valid
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Expected headings

  • H1 Terminology
  • H1 Usage
  • H1 Epidemiology
  • H2 Risk factors
  • H2 Associations
  • H1 Clinical presentation
  • H2 Complications
  • H1 Diagnosis
  • H2 Diagnostic criteria
  • H2 Diagnostic clues
  • H1 Pathology
  • H2 Aetiology
  • H2 Location
  • H2 Classification
  • H2 Macroscopic appearance
  • H2 Microscopic appearance
  • H2 Immunophenotype
  • H2 Markers
  • H2 Genetics
  • H1 Radiographic features
  • H2 Plain radiograph
  • H2 Mammography
  • H2 Antenatal ultrasound
  • H2 Transoesophageal echocardiography
  • H2 Ultrasound
  • H2 CT
  • H3 Dual-energy CT
  • H2 Angiography (DSA)
  • H2 MRI
  • H2 CT/MRI
  • H2 Nuclear medicine
  • H3 PET-CT
  • H3 PET-MRI
  • H1 Radiology report
  • H1 Treatment and prognosis
  • H2 Complications
  • H1 History and etymology
  • H1 Differential diagnosis
  • H2 Clinical differential diagnosis
  • H1 Practical points
  • H1 See also

"Associations"

Line 20:1 · "Associations" is under the wrong parent heading (found under "Pathology").

"MRCP and ERCP"

Line 53:1 · "MRCP and ERCP" is not a recognised heading for this article type.

"Complications"

Line 79:1 · "Complications" is under the wrong parent heading (found under "Treatment and prognosis").
Oxford Comma
suggestion

"The average age of diagnosis of primary sclerosing cholangitis is 54 years (range 6-93), with increased occurrence in men (63%) 15. A large number of asymptomatic individuals are identified upon investigation of persistently deranged liver function tests. Symptomatic individuals commonly present non-specifically with fatigue. More specific symptoms include pruritus, jaundice or gastrointestinal bleeding 16."

Line 9:374 · Use the Oxford comma in 'pruritus, jaundice or gastrointestinal'.

"No medical therapy has stood the test of time, with ursodeoxycholic acid, immunosuppression, chelation and antifibrinolytic therapy unable to demonstrate consistent benefits over placebo 8."

Line 77:78 · Use the Oxford comma in 'immunosuppression, chelation and antifibrinolytic'.
Semicolons
suggestion

"IgG4 levels 4x normal; ratio of IgG4 to IgG1 of >0.24 17"

Line 107:29 · Use semicolons judiciously.